Isula is set in the La Kalsa district of Palermo, 500 metres from Fontana Pretoria, less than 1 km from Palermo Cathedral and a 2-minute walk from Via Maqueda. Popular points of interest nearby include Teatro Politeama Palermo, Piazza Castelnuovo and Foro Italico - Palermo. The guest house has family rooms.
All units feature air conditioning and a flat-screen TV. The units have a kettle, a private bathroom and free WiFi, while some rooms also offer a balcony and some have quiet street views. At the guest house, the units include bed linen and towels.
Popular points of interest near the guest house include Church of the Gesu, Palermo Central Train Station and Teatro Massimo. The nearest airport is Falcone-Borsellino Airport, 29 km from Isula.