Conveniently located in the Naples Historical Centre district of Naples, B&B Donna Luisa is located 1.1 km from MUSA, 700 metres from San Gregorio Armeno and 1.3 km from Maschio Angioino. It is set 500 metres from Museo Cappella Sansevero and offers a shared kitchen. The property is 1.1 km from Naples National Archeological Museum, and within 700 metres of the city centre.
All units feature air conditioning and a flat-screen TV. The units include a kettle, a private bathroom and free WiFi, while selected rooms also offer a balcony and some have city views. At the bed and breakfast, all units are equipped with bed linen and towels.
Popular points of interest near the bed and breakfast include San Carlo Theatre, Chiesa dei Santi Filippo e Giacomo and Palazzo Reale Napoli. The nearest airport is Naples International Airport, 9 km from B&B Donna Luisa.